All I can suggest is a Reset which will keep your personal stuff but remove all installed 3rd party programs, but I don't know if you will be able to access the advanced boot options from Safe Mode on your machine.
I have a machine on 1809 and another on 1803 and have found that the 1809 machine won't boot into those options from Safe Mode but the 1803 will.
Having created a Macrium system image, the 1809 machine is undergoing a Reset to see if it can then.
One other thing I've found which now doesn't work is a bcededit cmd which would have also cancelled Safe Mode - that is producing an error of Element not found on both machines and even after booting up with install media and selecting Repair your computer on the install screen which gives you the advanced boot options, although you don't get the option to reset from there.
From a Command Prompt (Admin) or Powershell (Admin) enter bcdedit and you are looking for what it gives as your Windows Boot Loader identifier.
It will be either {current} or {default}
Enter this cmd and if successful, reboot to see if it would boot normally.
I'm using {current} in the cmd but use whichever is for your identifier.
bcdedit /deletevalue {current} safeboot
I've seen on Google that others have also had the Element not found error but no solution to it.
This error must be specific to later versions of Win 10 as I'd previously successfully used the cmd after booting into Safe Mode using msconfig but was unable to access msconfig in that mode.
Not sure if that was just down to my machine or that version of Win 10 as you have been able to access msconfig in the version you are using.
If you are able to go the Reset route, create a system image onto external media first and you will need to make a note of any 3rd party program product keys for when you come to reinstall them.
Still_Game has posted this thread suggesting a program which may also help -
https://www.tweaking.com/forums/index.php/topic,6053.0.html